“Speed of the Sound of Loneliness” by John Prine is one of the best-known songs from his career. The track was released as a single in 1986 and also came out as a duet with Nanci Griffith. Listed below is the guitar tab for this track. You can use the song’s progression to play the song on your own. The song’s key is D. It uses the G, C, and D chords to form the melody. This fingerstyle accompaniment is easy to play once you get the hang of it, but will require a good deal of practice.